Viral hepatitis is one of the most common infectious diseases characterized by inflammation. It is also a great contributor to many deaths globally. Hepatitis can lead to the formation of liver cancer and cirrhosis.
Although the results of the above study sound potentially discouraging, most experts say there’s no need to freak out over the impact of CBD on the liver. While experts stress the importance of knowing the risks of taking health supplements, the amount of CBD the mice were exposed to is much higher than what most humans take.
CBD has been shown to have anti-fibrosis properties by eliminating cells that secrete collagen and cause fibrosis. It can also reverse alterations in the liver associated with alcohol-induced injury (9).
CBD Oil for Hepatic Encephalopathy
Unfortunately, there are no official dosage recommendations when it comes to CBD and the liver. Most clinical trials that suggest specific dosages of CBD have been performed on anxiety, chronic disorder such as epilepsy, and multiple sclerosis models in humans. No clinical study has yet investigated the efficacy of different doses of CBD on the symptoms of liver disease.
Ischemia is a very common injury that occurs as an aftermath of liver surgeries and liver transplantations. It involves major inflammation and is responsible for deaths in the case of transplants and rejections. Oxidative stress can worsen the condition.
CBD has been shown to have therapeutic effects in many major liver diseases, including viral hepatitis, fatty liver disease, ischemia-reperfusion injury, cirrhosis, fibrosis, and liver cancer.
On average, cannabis users ate more junk foods, soda, and alcohol than non-users , yet still had lower incidences of metabolic disease.
These scars cause permanent changes to the liver, making it ineffective, and eventually leading to more serious symptoms.
This causes damage to the liver cells, making them less effective at doing the job they’re meant to do. As the liver cells die, they trigger inflammation in the area, causing the liver to swell and become even less effective.
The body can generally tolerate small amounts of alcohol relatively well, however, large amounts are problematic to the body.
There are 3 different ways the liver can metabolize alcohol, the main one being a pathway called alcohol dehydrogenase. There are many steps to this process, but the most important thing to know is that it requires a lot of energy to function.
Modulating the ECS activity might have several therapeutic responses to health conditions and diseases (18) .
Alcoholism can induce hepatosteatosis (fatty liver disease), commonly known as alcoholic liver disease (ALD).
Pros and Cons of CBD Oil for Liver Damage
The side effects of these treatments have caused individuals to look for a supplemental approach to treating their livers.
The study also mentioned that CB1 receptor knockout mice treated with CB1 antagonists were resistant to diet-induced obesity (DIO) (19) .
One must also use discretion when using CBD and always discuss their dosage with physicians. CBD may cause liver injury when used in high dosages (43) .