According to a letter entitled “Marijuana and stoned fruit,” written by medical doctors from the University of California, San Diego, and published in the Annals of Allergy, Asthma, and Immunology on Feb. 2, 2018, a 24-year-old man who smoked marijuana daily visited their allergy clinic two weeks following an anaphylactic reaction after eating yogurt with hemp seeds.
A 2011 research report published in the journal Free Radical Biology and Medicine examined the potential role of CBD in various inflammatory-type conditions. George W. Booz, a professor in the department of pharmacology and toxicology at the University of Mississippi Medical Center, concluded in the report: “Inflammation and oxidative stress are intimately involved in the genesis of many human diseases. Unraveling that relationship therapeutically has proven challenging, in part because inflammation and oxidative stress ‘feed off’ each other. However, CBD would seem to be a promising starting point for further drug development given its antioxidant (although relatively modest) and anti-inflammatory actions on immune cells … .”
“Touching the plant can very easily develop a dermatitis, itching, and skin reactions,” he said.
Allergic reactions to CBD oil
People can also develop allergies to some of the terpenes found in cannabis. For instance, researchers from the Duke University School of Medicine found that about 20% of the 100 people they tested had an allergic skin reaction to linalool, whereas 8% had reactions to limonene. These kinds of contact allergies may not be common in the general population, but individuals who are employed in the production of cannabis products and CBD oil could be more at risk.
“This was his first known ingestion of hemp seeds. Immediately after consumption, he developed oral pruritus [itching] that progressed to shortness of breath, facial swelling, and pre-syncope [sensation prior to fainting],” the letter stated.
That being said, only male marijuana plants produce pollen, and are exceedingly rare in cannabis and hemp production because they produce less oil and CBD than female plants. Therefore, a consumer’s exposure to pollen would be extremely rare.
Though research is still limited in regards to many supposed benefits, in 2018 the FDA approved Epidiolex, a CBD oral solution, to treat seizures associated with two severe types of epilepsy, Dravet syndrome and Lennox-Gastaut syndrome.
Based on the recent studies, we know that the interaction of the skin with a CBD-based product can inhibit cell activation on the histamine response, which, when activated, leads to intense itching and inflammation. “However, purity of product and additives or other ingredients included in the product also matter and can have a reverse effect,” she says.
Although CBD oil is considered harmless, there is not enough evidence or studies to back up its true effectiveness in treating eczema. There are many other ingredients on the market that can help treat and prevent eczema, including ceramides. “Ceramides are lipids found in our skin that help retain moisture and keep the barrier function working,” explains Shamban.
Shamban also agrees. “Ingesting the product has to get through the entire digestive system to work inside out for inflammatory issues, whereas topically you can target the dermal cellular level if the product is pure and able to penetrate.”
CBD purity: How does this affect eczema, if at all?
According to Mary’s Nutritionals’ Chief Scientist, Jeremy Riggle, Ph.D., CBD has demonstrated the potential to help mitigate the symptoms of eczema, particularly pain, itch and inflammation. “All these responses are modulated by the endocannabinoid system, [which] plays a crucial role in skin pathogenesis and the maintenance of homeostasis,” he says. The endocannabinoid system helps regulate different processes including mood, memory, pain, appetite, stress, immune function and more. “CBD interacts with this system and may help the skin re-establish or maintain homeostasis, the result, in this case, being a reduction in symptoms associated with eczema.”
Although CBD oil is still a new industry in terms of medical applications, “it has been long observed and known since the first dermatology textbooks that cannabinoids do possess strong anti-inflammatory benefits as well as calming anti-itch properties,” says Shamban. “Until recently, there was no research to understand how and why, but it has been more ‘anecdotal reporting’ and community consensus, not clinical.” According to Shamban, CBD is not harmful against certain skin conditions, but doctors are unsure of how helpful it is. “Truthfully, there is probably a direct connection and benefit [of CBD oil for eczema], but the range of cannabis topicals in terms of type, amount and delivery systems … makes it more complicated for us as medical professionals to give accuracy on the specifics,” she says.
Atopic eczema is a chronic disease where the skin barrier has become leaky, and inflammation occurs.
Eczema is not contagious, but doctors are not 100 percent sure of its cause. “We don’t really know its exact cause, but it is specific to genetic disposition, immune system and a potential range of environmental triggers that can cause an inflammation response which, in ‘overdrive,’ creates the physical symptoms of these conditions,” says Shamban.
Any of these could be signs of anaphylactic shock, which can be life threatening. Thus, you need to get help as soon as possible.
Alex Malkin is CBD-enthusiast, researcher, and co-founder of CBD.market, a trading platform for CBD products and educating.
If you are interested in trying CBD products but are concerned you might be allergic, you should consider making an appointment with your doctor or an allergy specialist. They’ll be able to conduct a test that will let you know for sure if you will react to CBD oil.
Taking CBD oil should make you feel better, not worse. While allergic reactions to CBD are rare, they still occur. Take the necessary steps to ensure that taking CBD will benefit your health and wellbeing.
Allergy and Type of CBD Oil Product
If you are using a topical CBD product, some of the CBD oil allergy symptoms that you might notice include:
Should you notice any of these signs or symptoms while taking CBD products, it’s advised that you stop using them immediately. You might also consider making an appointment with your physician or taking an allergy medication to help with the symptoms.
It’s possible that incredibly serious allergic reactions to CBD can occur. If you experience any of the following symptoms, it’s in your best interest to get medical assistance:
Since CBD is derived from the hemp plant, it does contain some of the common elements that trigger allergies. These include pollen and histamine. While it is possible for someone to have an allergic reaction, it is rare.
CBD is extracted from plants, so it’s possible that you can experience symptoms that are similar to having seasonal allergies. If you have an allergic reaction to CBD oil, it’s possible that you might experience one or more of the following: