When you ingest CBD, it interacts with a system of enzymes known as Cytochrome p450 (CYP450). These enzymes are responsible for the metabolism of drugs from pharmaceutical medications. CBD is the inhibitor of CYP45, preventing these compounds from being properly processed in the liver.
Marijuana naturally contains significant concentrations of THC, so CBD oils extracted from marijuana strains — even the CBD-rich ones — will consider a higher amount of THC than a hemp-derived product. Hemp plants usually contain less than 0.3% of THC, containing higher levels of CBD.
Since THC can be habit-forming, it’s important to know the difference between CBD oil sources.
Side Effects of Taking too Much CBD
Compared with the placebo group, subjects treated with CBD reported lower anxiety levels and cravings from heroin addiction withdrawals.
Because of the negligible concentration of THC, hemp-derived CBD oils aren’t addictive. They’re also legal on a federal level; you can easily find CBD oils online and over the counter in dispensaries, vape stores, wellness centers, and major pharmacies.
We also feel obliged to cover one important issue regarding CBD — potential interactions with drugs.
Some studies also mention its potential as a supportive agent in overcoming the withdrawal symptoms after cessation.
CBD won’t make you see things or make you feel high, and it is not been identified as being addictive! But be careful when buying CBD products. While CBD products have many potential benefits, the last thing you want is to purchase CBD products with a THC level over 0.3%, since that could put you at risk of going over the legal limit and getting in trouble.
Now, here’s where the confusing part begins. Many people use terms like hemp, cannabis, and marijuana interchangeably. And that’s a big problem, since they are actually chemically different substances on the cannabinoid molecule level, with different legal statuses as well. It’s therefore very important to know the difference between hemp and marijuana. This will help you understand why you can’t get high from hemp-extracted CBD, but you can get high from marijuana extracted CBD that contains THC over 0.3%.
Cannabidiol (CBD) is having a major moment. Whether it’s a water-soluble drink concentrate or infused in gummies, honey, chocolate, or suppositories, CBD is showing up in almost everything you can imagine. And it’s not just for consumption: CBD is also taking over the beauty industry. From skin cream to cleansers, a variety of CBD-infused products are cropping up in stores everywhere. Cleansers don’t make sense to us, because why would you apply expensive CBD and then immediately wash it off before your skin has a chance to absorb it?
How to Choose CBD Products
Anxiety and depression can reduce your quality of life, just ask anyone you know who deals with anxiety or depression. Anxiety and depression are serious mental disorders, and both are very prevalent in this country. Thankfully, CBD appears to have promise in treating both anxiety and depression, and some of our customer reviews are very telling. In fact, CBD seems to help people fight fears of public speaking and/or social anxiety.
Recently, CBD has been proposed as an addiction treatment. So, can CBD really help fight addiction? Well, studies suggest that CBD may help treat addiction and prevent relapses in substance abusers. How does it work? While we don’t know for sure, the CB1 and CB2 receptors are filled with opioids and when you fill those receptors with CBD instead the cravings of opioids are not as prevalent. So, it seems that, by helping reduce stress and anxiety, CBD improves your quality of life sufficiently to protect addicted individuals from vulnerability and neurotoxicity.
Do you always have trouble getting a restful night? Often, people with anxiety, depression, and inflammatory diseases have issues sleeping . People who are going through treatments for cancer also have difficulty sleeping. CBD may help reduce insomnia and other sleeping difficulties as studies outline the relaxing effects CBD creates. This is likely because of CBD’s potential to reduce pain and anxiety, which in turn makes it possible for users to improve their sleep quality.
CBD isolate only contains pure isolated CBD extracted from the hemp plant, so it is technically the purest form of CBD, although isolate users miss out on other beneficial substances found in cannabis plants they prefer isolate which is usually found in gummies. Full-spectrum CBD contains all the chemical compounds found in the extracted hemp plant, including trace amounts of THC. And broad spectrum CBD contains no THC but preserves all other cannabinoids.
CBD has potential as a treatment for cannabis dependence. Photo by: Gina Coleman/Weedmaps
While all signs suggest that CBD is not addictive, someone who takes large amounts of CBD on a daily basis could experience side effects. Photo by: Gina Coleman/Weedmaps
CBD is effective in reducing drug use, and also reduced common side effects of drug dependency, such as anxiety and impulsivity. Photo by: Gina Coleman/Weedmaps
Despite growing acceptance and recognition of CBD’s potential benefits, concerns remain about the cannabinoid’s power to cause addiction. This may be due to confusion between non-intoxicating CBD and its intoxicating counterpart, THC. Because of the way CBD interacts with receptors in the body’s endocannabinoid system, it doesn’t have the psychoactive effects of THC. In fact, CBD basically blocks THC’s access to those receptors found throughout the nervous system, thereby reducing some of THC’s effects.
Evidence suggests that CBD could also be used to help combat the adverse effects of THC, such as cannabis withdrawal symptoms. In a 2013 report, researchers administered CBD to a 19-year-old woman with cannabis withdrawal syndrome over a ten day period, which effectively resulted in reduced withdrawal symptoms. Another study, conducted in 2010 and published in Neuropsychopharmacology, examined a total of 94 cannabis users to see what role CBD-to-THC ratios played in reinforcing the effects of drugs and implicit attentional bias to drug stimuli. Compared with smokers of low-CBD strains, the study found that smokers of high-CBD strains showed reduced attentional bias to drug and food stimuli, as well as lower self-rated liking of cannabis stimuli. The research team concluded that “CBD has potential as a treatment for cannabis dependence” and could offer a potential treatment for other addictive disorders.
This non-intoxicating cannabinoid has also shown promise in human models. A May 2019 study, published in the American Journal of Psychiatry, found that CBD could be effective in reducing cravings associated with heroin addiction. To conduct the study, researchers recruited 42 adults who had been using heroin for an average of 13 years. The subjects were divided into three groups: one group was given 800 milligrams of CBD, another 400 milligrams of CBD, and another a placebo. Compared with the placebo, those who were administered CBD significantly reduced both the craving and anxiety induced by the drug cues.
While CBD doesn’t produce the kind of intoxicating effects THC is known for, it’s important to consider any possible CBD oil side effects.