In robust Phase 3 studies with 516 patients with either seizure type, Epidiolex, taken along with other medications, was shown to be effective in reducing the seizure frequency when compared with placebo.
For more information see: Marijuana
Which states / territories allow recreational use of marijuana?
Long-term, heavy use of marijuana (THC) can lead to a condition called cannabinoid hyperemesis syndrome (CHS). In this syndrome, persistent nausea, vomiting, and stomach pain can occur in people who have previously smoked marijuana long-term (six months or more). Dehydration, electrolyte disturbance, and acute kidney failure can occur. Not all heavy users of cannabis will develop this condition. Researchers think it is much more common in the U.S. than previously thought, especially with continued legalization of recreational marijuana.
Consumption of marijuana leads to a psychoactive drug effect. Do not drive, operate machinery, or perform other hazardous activities while using cannabis (marijuana). It may cause dizziness, drowsiness, and impaired judgment.
States that have legalized marijuana for recreational or medical consumption have laws in place that make it illegal to drive under the influence of marijuana; review each states law carefully.
Tetrahydrocannabinol (THC), a component of marijuana, acts both centrally and peripherally on endogenous cannabinoid receptors. Activation of cannabinoid receptors affects serotonin release, increases catecholamines, inhibits parasympathetic activity and inhibits prostaglandin biosynthesis.
Dosages of Marijuana Should Be Given As Follows:
What Are Dosages of Marijuana?
The United States (U.S.) Drug Enforcement Administration (DEA) classifies marijuana as a Schedule 1 substance under the Controlled Substances Act (CSA). Schedule I drugs are recognized as having a high potential for abuse with insufficient evidence for safety and efficacy with no currently accepted medical use for treatment in the U.S.
In October of 2009 the U.S. Justice Department announced that it will no longer enforce federal drug laws on persons who use marijuana for medicinal purposes or their sanctioned suppliers, as long as state laws are followed.
Marijuana can be used to decrease intraocular pressure, analgesia, anti-vomiting (antiemetic) effects and as an appetite stimulant.