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Advocates believe there are many potential health benefits, but clinicians say more research needs to be done.

CBD is the abbreviation for cannabidiol, one of the many cannabinoids, or chemical compounds, found in marijuana and hemp.

Most of the products claim to ease pain and anxiety. But whether or not these products actually contain the amount of CBD they advertise is up for debate, since they’re not approved by the FDA.

Arthritis Foundation offers guidelines for CBD use

The law depends on where you live, and whether the CBD comes from hemp or marijuana. The Farm Bill of 2018 legalized hemp. Marijuana is trickier because the federal government still considers it an illegal drug, although states have their own swiftly changing laws. Some states have legalized recreational use of marijuana, while others have legalized medical marijuana. Still others have introduced CBD-specific legislation.

Interest continues to grow. Last year, the federal government pledged $3 billion to research CBD.

Currently the Food and Drug Administration has only approved one CBD product, a prescription drug called Epidiolex to treat two rare forms of epilepsy. In July, the FDA expanded what the drug is approved to treat, saying it can also be used for seizures associated with tuberous sclerosis complex.

Advocates say CBD, or cannabidiol, which comes from hemp and marijuana, can help with anxiety, pain relief and provide a slew of other benefits. And while many experts agree that CBD has potential, there are still a lot of unknowns.

(Photo by: Gina Coleman/Weedmaps)

The relationship between THC and CBD is complex, but in short, CBD appears to minimize some of THC’s less desirable effects, such as paranoia , heart palpitations, and impaired thinking. A combination of THC and CBD may offer enhanced therapeutic value to patients . This phenomenon of cannabis-derived molecules working more synergistically together than they do in isolation is commonly referred to as the entourage effect .

Harlequin : This cultivar was bred by crossing classic landraces from Nepal, Switzerland, and Thailand. Its consistent 5:2 CBD to THC ratio ranks it among CBD-rich staple cultivars.

Epilepsy and seizures

Concentrates : CBD can also be purchased in concentrate form, including raw CBD oil, cartridges, vape pens , syringes, and more. Concentrates bridge the gap between CBD flower and CBD isolate.

CBD has some other very important roles outside the ECS. For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A) in mice, which may explain its supposed effects on depression and anxiety . It also acts at the peroxisome proliferator-activated receptors (PPARs) in mice, which may indicate its usefulness in fighting inflammation.

CBD’s actions within the brain and body are quite complicated. It’s very likely that the beneficial effects of CBD operate through diverse biological pathways, rather than by a single action. More research is needed to fully understand the mechanisms by which CBD relieves ailments such as seizures .

(Photo by: Gina Coleman/Weedmaps) Photo by: Gina Coleman/Weedmaps