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cbd oil and cirrhosis

However, the recent 2019 study on mice showed that high doses of CBD can damage the liver — causing widespread sensation all over the media.

To this day, studies on cannabinoids and their effect on liver cancer show that cannabinoids can both prevent the dividing of tumor cells and kill cancer cells while protecting the healthy ones. Besides stopping cancer proliferation, there are several mechanisms CBD uses to help tackle liver cancer.

The Study on CBD and the Liver of Mice

The optimal amount of CBD for each individual depends on factors such as weight, metabolism, age, gender, the severity of symptoms, and previous history with CBD products.

In the next section, we elaborate on the potential therapeutic uses of CBD oil for liver function.

High-quality full-spectrum CBD oil could be beneficial in a range of disorders that involve liver dysfunction and might help replace the long-term use of other medications.

Note, the study cited in the article was very small with children under physician care but if you are a liver patient it is a cautionary note if you are considering CBD oil. We are not aware of any research that would suggest using it more broadly but consult your doctor.

Because CBD oil is not considered a drug, it can be a common additive in many products. This includes e-cigarettes (vape oil), lotions and various herbal supplements. It has also been shown to relieve symptoms of different disorders like epilepsy, anxiety and multiple sclerosis.

As determined by the studies done on Epidiolex®, CBD is metabolized by the liver. People with nonalcoholic steatohepatitis (NASH) are encouraged to limit over-the-counter (OTC) medications to avoid stressing the liver.

What is CBD oil?

To further complicate the question, products with CBD oil may not give the exact amount listed on the package . Depending on the brand, the consumer may be using much more or less than they think. This is especially true of OTC supplements and e-cigarettes.

Always consult with a trained physician to develop the medical cannabis plan best suited for your needs.

To find the most effective form of relief from your symptoms, be sure to choose the cannabis ingestion method that’s ideal for your condition. Not sure which type of CBD is best suited for you? Cirrhosis patients typically find the most relief from the following methods:

How does CBD work to improve the endocannabinoid system? Since the endocannabinoid system experiences a lack of functioning when liver damage occurs, cannabinoids like CBD help “turn on” this system. Brain function becomes normalized and liver enzymes can restore, inhibiting fatty tissue from growing over this vital organ instead.

The Best CBD Products for Patients With Cirrhosis

Want to learn more about how you can benefit from medical marijuana use? At, we connect you with the resources necessary to make the most informed decision as a patient. Browse our extensive database or find out more about various diseases or medical cannabis resources by browsing our site today!

Cannabidiol (CBD), one of the more than 85 cannabinoids found in marijuana, produces many promising effects for those experiencing the complications that arise from liver damage or disease. As a non-psychoactive constituent of cannabis, patients reap the benefits of this substance without experience hallucinogenic effects.

In patients with severe liver damage or for those with cirrhosis, the lipid signaling molecules mediated by CB1 and CB2 receptors are abnormally low or absent within the endocannabinoid system. This irregularity causes cell damage or heightened inflammation responses that lead to fat accumulation in the liver. Because the endocannabinoid system cannot regulate appropriately in patients with liver damage or disease, patients miss out on the potentially therapeutic benefits offered by a normalized system.

Although researchers are still learning the full functionality of the recently discovered endocannabinoid system, scientists and doctors alike realize how significant this system is in ensuring proper bodily regulation. CB1 and CB2 receptors guide the various cannabinoids responsible for guaranteeing regulated functions. In patients with cirrhosis, the endocannabinoid system and its receptors experience complications that inhibit healthy inflammatory responses.