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cbd oil antioxidant

The unpaired electron in the free radical corrupted molecule attracts another electron from a healthy molecule, triggering a chain reaction that leaves us with a bunch of deteriorated molecules. Since these molecules are part of our cellular tissue, in all its differentiations, the result of this process is having one or more organs or body parts slowly “ageing” or even quickly getting sick.

Every living creature hosts a lifetime war between the “good” antioxidants and the “bad” free radicals. Over the last 20 years, this war was often under the media spotlight. Consequently, the general public became concerned and tried to increase our collective fruit and veggie intake. Free radicals are bad for our health—that’s what we all understood—and unfortunately, they are going to win the war, sooner or later. In this article, we take a look at the battle between free radicals and antioxidants that constantly dwell inside our body, examining if, according to research, CBD and other cannabinoids might be our allies.

Could CBD, THC, and other cannabinoids be our future allies in the lifetime war between antioxidants and free radicals? Early research suggests that cannabinoids have antioxidant and neuroprotective properties. Now it’s time for clinical trials.


Too many free radicals in the body, for any reason, can trigger minor diseases and severe conditions as well, such as cancer, Alzheimer’s or Parkinson’s, atherosclerosis, heart disease, and stroke. On the other hand, we all know through advertising that our natural and “harmless” skin ageing is mainly caused by free radicals. Brain cells use a significant amount of energy to do their job. That creates free radicals and oxidative damage at a neuronal level, leading to age-related decline.

Humans need to convert food into energy to survive. When our metabolic processes create energy, they also generate waste products. Some of them are molecules of some biochemical compound containing an unpaired electron, namely, free radicals. Free radicals in our body are also generated from external factors, such as stress and toxins, be they inhaled, ingested, injected, or absorbed by the skin.

An antioxidant is a natural substance that inhibits oxidation, the chemical reaction that produces the free radicals damaging the cells. We are able to produce our own antioxidants up to a certain level, yet not enough to neutralise all of the harmful effects of external factors like pollution, junk food, smoke, and many more. That’s why it’s important to harness a lot of antioxidants from food, even if it is hard to tell how much we actually need during every stage of life. Antioxidants are an important part of any diet for maintaining good health and proper function since it’s proven that the damage to “oxidised” cells leads to illness and chronic disease.

Antioxidants give out electrons to lonely electrons in free radicals, thus creating a pair that stabilises the molecule and prevents the chain reaction effect made by stolen electrons from other molecules that degrade cellular functionality. Antioxidants are substances like ascorbic acid (vitamin C), vitamin E, glutathione, lipoic acid, uric acid, carotenes, and coenzyme Q10.

Fascinatingly, in laboratory studies, CBD has been found to be an antioxidant, with even more antioxidant quality than Vitamin C (ascorbate) or Vitamin E (α-tocopherol)! As early as 1998, the National Institute of Mental Health and the National Cancer Institute began discovering that CBD works as an antioxidant and neuroprotectant. Then in 2000, the National Institute of Mental Health performed a follow-up neuronal culture study that found CBD and other cannabinoids were more powerful than Vitamin C and Vitamin E in protecting neurons exposed to hydroperoxide toxicity.

The antidote to free radicals is antioxidants. Antioxidants disable the free radicals’ abilities to steal electrons by donating their own electrons, thus keeping the free radicals away from our healthy cells and DNA particles. In doing so, they break the chain reaction that can eventually lead to degenerative diseases. This process is why antioxidants are an imperative part of protecting our brains and bodies from oxidization.

The marker of good health is how well our body manages free radicals, which can come from stress and toxins in the environment, including UV rays, pollution, and tobacco smoke. Free radicals are also generated as natural byproducts from our cells’ natural processes. For example, when our immune system fights off viruses and bacteria, it creates a oxidative burst of free radicals in an attempt to kill the invaders and any damaged cells.

The phytochemicals in plants have special antioxidant properties, according to Harvard Medical School. Vitamin C, for example, will donate electrons to a free radical – and then the phytochemical hesperetin (found in citrus fruits) will restore the Vitamin C back to its antioxidant capabilities!

CBD: A Super Antioxidant Patented by the US Government

Our bodies create some antioxidants like alpha lipoic acid and glutathioine. In addition, our diet’s minerals and vitamins are a rich source of antioxidants, such as Vitamin C, Vitamin E, zinc, copper, and selenium. Cartenoids like lutein from kale are also antixodiants, along with flavinoids from green tea, cocoa, blueberries, apples, and onions.

As well, every ingredient in our Revive line has antioxidant effects. We combined full spectrum CBD oil with the antioxidant-rich orange oil, sage, ginseng, as well as the terpenes limonene, pinene, and humulene. The cherry on top is Vitamin B12, whose antioxidant qualities have been shown to protect oxidative stress from an immune system response.

Master of Science (MS)

College of Education and Human Services


Nutrition and Food Studies

The Cannabis industry has seen immense growth in recent years and research on this plant and its constituents has been growing to keep up with industry demand. The majority of research has focused on commercial-scale products and industrial processing, but there is a lack of research on the smaller scale manufacturing side of the Cannabis industry that includes homemade Cannabis products. Popular Cannabis products are oil-based tinctures that are made by infusing Cannabis plant material in a heated source of edible oil. The types of oils used for this process vary, and there is not an established standardized oil type that has been shown to be the optimal choice for reaping the most benefits from Cannabis infusion. The goal of infusing Cannabis in oil is to extract the desirable potentially neurologically active cannabinoid plant molecules that also serve as antioxidants, specifically cannabidiol (CBD). To determine the effect of oil type on extraction ability of Cannabis, different oil types were used to infuse a high-CBD strain of Cannabis and measure antioxidant potential, total phenolic content, and CBD content of the resulting oils. Hemp oil, MCT oil, and olive oil were used as infusion solvents for the ground decarboxylated Cannabis flowers. Consistency in the protocol was followed for the strain of Cannabis, decarboxylation process, grinding process, heated infusion process, and storage conditions. Additionally, control standards were established by implementing the heating process for the oils without Cannabis infusion. Antioxidant potential was assessed using Trolox Equivalent Antioxidant Capacity (TEAC) assay, and total phenolic content was assessed using Gallic Acid Equivalence (GAE) assay. CBD content of the CBD oils was assessed using high-performance liquid chromatography with ultraviolet detection (HPLC-UV). For antioxidant potential, hemp CBD oil had the greatest antioxidant potential, but the other CBD oils had a significant increase in antioxidant potential compared to their control oils whereas hemp CBD oil did not. For total phenolic content, olive CBD oil had the highest total phenolic content. For CBD content, hemp CBD oil and olive CBD oil had the highest CBD content.