Mitochondria exist in every cell in the body other than red blood cells.
There are "acid" and "neutral" forms of every cannabinoid molecule. Early man knew the difference and would either just eat the cannabis raw, or heat it to convert to the neutral or "active" forms of the cannabinoids.
Benefits of THCA?
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However, since THC-A is obviously “made” quite easily in nature, more recently we have been able to witness just how patients benefit that have a variety of disorders, including those with cancer, seizures, Myasthenia Gravis, and other neurological disorders and myopathies.
Mitochondrial disease also links to a wide range of other diseases. Mitochondria play a role in proper neuron functioning, as neurons require a high amount of energy to function properly. Mitochondrial failure in neurons can lead to neurodegenerative disorders, such as Alzheimer’s and other dementias. Mitochondrial dysfunction is also evident in many other ailments, including:
The effectiveness of current treatments for mitochondrial disease varies from patient to patient and depends on the type of affected cells and the severity of their disease. In general, those with milder mitochondrial disorders will experience more success with treatment than those with severe mitochondrial disorders. Some patients can experience symptom relief and slowed progression of mitochondrial disease with treatment programs tailored expertly to their specific set of symptoms. For other patients, however, personal treatment plans that should be effective do not result in benefits or improvement.
Effects of Mitochondrial Disease
Mitochondrial disease is a complicated group of ailments that affects each patient differently. Some mitochondrial disorders are severe or even fatal, while others have a much smaller impact on daily life. For many people suffering from a mitochondrial disease, their symptoms may change dramatically from day to day, making it challenging to establish a healthy lifestyle. Mitochondrial disease is also connected to the development of many other more debilitating diseases. Therapy and other treatments for mitochondrial diseases have varied success and can sometimes cause a patient’s condition to decline.
For some patients, treatment for mitochondrial disease will not be effective at all or may cause their condition to decline. Treatment for mitochondrial disease also cannot reverse any damage that has already happened to cells. So, patients who have already sustained neurological damage or other debilitating effects may not find treatment beneficial except to stabilize their current condition.
A 2012 study on aging showed cannabinoid interaction with mitochondria could suppress neuroinflammatory processes that contribute to aging and slow neurodegeneration. It improves motor and cognitive impairment that result from neurodegenerative diseases, as well as slowing natural cognitive decline. This study also echoed the consensus that cannabinoids can regulate mitochondrial activity to preserve homeostasis in cells.