Bottom line: I do believe that it may have potential health benefits. However, until we have more studies to prove effectiveness that outweighs side effects, studies to know its potential interactions with other medications, and that we have regulatory controls to ensure high quality products (devoid of harmful contaminants), I cannot recommend it.
Donald E. Thomas, Jr., MD, FACP, FACR, RhMSUS, CCD
With our current opioid crisis along with the increasing approval of the use of medical cannabis in the United States, this is a timely and appropriate question. Cannabis (also known as marijuana) is the most commonly used illegal drug worldwide (at least illegal in most areas). The compound called delta 9-tetrahydrocannabinol (THC) is responsible for its effects that make people feel “high”. Another compound in cannabis is cannabidiol, known as CBD for short. CBD does not have the “high” exerting effects of THC but is thought to have medicinal effects partly due to its attachment to cannabinoid receptors. These receptors are located on the surfaces of cells throughout the body to include the brain, nerves, and cells of the immune system. Therefore, it is not surprising that CBD may potentially have beneficial health properties. .
After being denied Orencia by my insurance for 2 years I was really looking for anything that could help. I tried gummies 1st. (Really REALLY don't waste time with gummmies) I was skeptical. I did notice that my brain fog drifted off and my spine pain cleared. BUT my joints still hurt.
My compound pharmacists store sells CBD so I called to ask their nutritionist if she could explain to me more about it. She and the lead pharmacist were a wealth of information for me.
I started using the "green" formula, which is considered the rawest form. I noticed right away that my brain fog lifted and my spine pain melted away. It did help me with connective tissue the longer I used it.
The exciting thing is that after a month or so I started to develop saliva again! My dentist even asked me what I was using because I had an over abundance of it.
Then when I went to my eye doctor HE asked me what I was using. I had near to no abrasions on my eyes and I clearly had tearing.
My Cornea Specialist- the same thing. My Cornea Specialist has been documenting it closely as some of his other patients that have had the same results.
My Rheumy has had so many patients say they have had good results as well.
She just wishes that there were some numbers on it's use.
I really do wish that there could be some legitimate testing done because I'd love to know more of how it works.
I do have to say that my severe joint issues weren't helped as much as I wanted. I'll take spit, tears and no spine pain off my plate as a much blessing!
I use a product that's grown in Europe so no pesticide and the product has already been tested by the feds.
It's a buyer beware kind of thing and as with anything you take, herbal or pharma, you have to pay attention to your body.
P.S. I'm a pretty conservative kinda gal. I really did some homework before starting to use it because of the bad reputation anything hemp has been.
I have included only a few paragraphs from this article, but be sure to head over to the Sjogren’s Syndrome Foundation to read it in its entirety.
Amy Junod: Ditto for me! Sleeping well and therefor no brain fog or body pain.
Many people know that cannabis can cause dry mouth as a side effect. But what about CBD?
A 2013 study for the International Journal of Ophthalmology investigated. It tested the effects of omega-3 supplementation vs. placebo on patients with dry eye symptoms.
So, what is the truth about CBD oil for Sjogren’s syndrome? Is it really effective, or are companies just cashing in on the latest healthcare craze?
Traditional Sjogren’s Syndrome Treatments (Not CBD)
Dry mouth can cause the following symptoms:
Hemp seed oil may be more suitable as it is rich in omega-3 fatty acids, which appear to benefit dry eyes. However, research is minimal, and whether it translates to patients with Sjogren’s syndrome remains to be seen.
CBD influences the production of a number of inflammatory modulators to produce anti-inflammatory effects. It can, therefore, help to relieve pain and may even slow disease progression.
A 2006 study for Experimental Biology and Medicine tested anandamide’s effects on the salivary glands of rats. It found that injecting the compound directly into the rats’ submandibular glands reduced their saliva production.
The recent elections in the United States legalized marijuana (medical or recreational) in a number of states. There are now 28 states where marijuana is legal for medical use, and 8 states (plus Washington DC) where it is legal for recreational use. With the attention being focused on the medical applications of marijuana, one may ask if there is any evidence that medical marijuana could be used to treat Sjogren’s Syndrome.
The short answer is that there is very little direct evidence that marijuana can be used to treat SS. Restrictions on cannabis research in many countries including the United States has meant that research on cannabis has moved quite slowly. In addition, most of the research has focused on cancer treatments and pain management. However, there is also little evidence that helminths or low-dose Naltrexone are effective SS treatments due to the general lack of well-funded research for SS. As a result, it makes sense to take a step back and look at what research is available for general inflammation and other autoimmune diseases.
So where does that leave us SS patients? While there is limited research, the increasing availability of marijuana has lead to anecdotal success stories from the online community. In addition, there has been an increase in CBD products being made from industrial hemp, which has very low THC content and can be legally imported into the United States from other countries. Unfortunately, there are very few regulations on these products outside of states where they are legal, so there is a danger in purchasing unknown and untested products online. As a result, for those who live in states or countries where medical marijuana is legal, I would recommend going through government-approved dispensaries instead of ordering CBD derived from hemp oil online. Many marijuana dispensaries now sell oils and other products with high CBD and low THC content. Do note that one common side effect of marijuana is dry mouth, which is unfortunate for us SS patients. Hopefully this side effect will be less problematic when using CBD oil.
CBD, unlike THC, has few psychological side effects, and is believed to moderate the effects of THC. In lab studies, it has also been found to have anti-inflammatory effects, as well as modulating effects on certain immune cells. As a result, CBD is a major focus for the limited medical research being carried out with cannabis.
The full article provides more details, and while there are positive signs, particularly in a lab, there is not enough real-world evidence with human patients to reach a verdict. The article does explain the history of medical cannabis (going back to 4000 BC) and the progression of current medical work. While marijuana contains over 500 different components, it is the cannabinoids that have been of greatest interest. The two main cannabinoids for purposes of medical research are tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the cause of most effects that marijuana is known for, including a feeling of relaxation and sometimes anxiety. THC also has some medical uses today, including Dronabinol, a prescription drug used to treat nausea caused by cancer.