For example, inflammation is one of the most important processes carried out by your body’s immune system. This helps to isolate areas that are infected and prevent the toxic components from spreading to other parts of your body. CBD includes anti-inflammatory elements that help reduce your immune system’s inflammatory response.
Also, CBD can help modulate or suppress the functioning and secretion of cytokines. These are large groups of proteins, which are secreted in your body’s immune system. It helps to regulate inflammation, immunity, and the production of white blood cells. All this will help your immune system work smarter and keep you healthy..
Cannabidiol can help boost your immune system. In fact, research has proven that CBD includes anti-inflammatory properties and can work as an immunosuppressant and immunomodulator.
CBD and Your Immune System
Your immune system is also tasked with detecting cells that aren’t working correctly and eliminating them from the body. Your immune system must eliminate these cells so they don’t continue to multiply, which could lead to tumors.
Your body is exposed to an array of diseases, infections, viruses, and bacteria each day. If you had no immune system, even the most common illness might be fatal. The arrangement of the cells, tissues, and organs that work together to eliminate foreign particles and foreign invaders is your immune system. It is what keeps you healthy.
If you want to achieve the potential benefits that CBD offers for your immune system, it is necessary to find a quality and reputable product. Be sure to take time to find a company that provides reputable products for affordable prices.
The most common product extracted from CBD is CBD oil. Since it is still somewhat of a new product, researchers are still learning more about it. However, according to current studies, cannabinoids, like CBD edibles and cannabis oil, can help boost your immune system and promote better health.
THC and CBD affect both CB1 and CB2 receptors. These receptors are important because they are our prime neurotransmitters. CB1 receptors regulate pain, coordination, and brain function such as mood, appetite, and thoughts, while CB2 receptors influence immune response such as inflammation.
CBD, cannabidiol, interacts with both receptors indirectly. CBD wills the body to create more endocannabinoids instead of replacing them. CBD can suppress and boost immune system activity. How so? CBD’s effect on you is completely dependent on your body’s function. Past studies show that CBD encourages white blood cell production in immunodeficient patients, helping boost the immune response in persons with HIV. Other trials have shown CBD to suppress immune response, such as inflammation, in patients with autoimmune disorder such as rheumatoid arthritis. Think of CBD in terms of a modulator, rather than a boosting or suppressing agent.
As we discussed in our last article, marijuana effects healthy and compromised immune systems differently. While healthy folks using marijuana experience a suppressed immunity, those with autoimmune diseases can receive benefits from marijuana intervention. Today, we will look closely at how the individual compounds, THC and CBD, affect the immune system and what you can expect from different strains.
Our central nervous system, i.e. the endocannabinoid system, maintains the body’s daily function and wellness. The endocannabinoid system achieves homeostasis through endocannabinoid production and endocannabinoid receptors CB1 and CB2. The endocannabinoids and receptors communicate through a process called binding and work together to control our immune system. Sometimes, in the case of autoimmune disorders, the endocannabinoids our body produces fail to function properly. When this happens, our body will accept cannabinoids (from marijuana) in place of the failed endocannabinoids.
THC is notably active in response to immune function. THC actively binds to CB1 and CB2 receptors. THC plays a major role as a psychoactive chemical when binding to CB1 receptors that control the mind’s function. CB1 receptors tell the body whether it is experiencing pain which can be negated by THC. The main impact upon the immune system is through the binding process in CB2 receptors. In a patient study performed in 1994, researchers confirmed THC activated immunosuppressing proteins after binding to CB2 receptors and influencing T-cells. This is great news for people battling autoimmune disorders, such as rheumatoid arthritis and Crohn’s disease, because it will help with inflammation of the body. In 2011, the University of Louisiana conducted a study on the effects of THC on monkeys with the simian immunodeficiency virus (SIV). The results were astonishing. 28 days before the monkeys contracted SIV, they were given doses of THC. This reduced the viral load and extended the life of the primate. In 2014, the same team gave the monkeys THC 17 months before the SIV infection stage. This not only increased T cell numbers, as well as decrease the viral load, but protected the apes against viral intestinal damage SIV patients usually suffer. Through theses tests, researchers are realizing the potential of THC as an immunostimulant.
While much is yet to be discovered on perfecting the balance of THC and CBD for immunotherapy purposes, we know that marijuana does help with many other symptoms that immunodeficient and autoimmune disease patients face. While cannabis can tackle many problems with serious diseases, it has yet to show benefits during times of flu illness.
Research assessing CBD’s effect on cancer patients whose immune system is severely compromised suggested that patients are in a better state to fight cancer when using CBD. An example of this is the study published in the British Journal of Clinical Pharmacology that found that CBD may be effective in reducing tumour growth in certain cancers. Another study found that cannabinoids in high doses prompted the body and immune system to kill cancer cells through a biological process called apoptosis. Apoptosis is activated in a healthy immune system when infectious cells as detected. This study’s discoveries are extremely significant considering cancer cells are characterised by their capability to avoid apoptosis, this then enables them to proliferate throughout not only the immune system but the entire body.
There has been research that has demonstrated that cannabinoids such as CBD can interfere with the release of cytokine, which are the proteins involved in causing inflammation in people with chronic illnesses. There is a suggestion that CBD may play an important role in managing how the body operates when dealing with autoimmune diseases such as Multiple Sclerosis, HIV/AIDS, Parkinson’s and Rheumatoid Arthritis. Autoimmune diseases are characterised by an immune system exaggerating the reaction to non-threatening internal events which results in the immune system attacking healthy cells in the body.
Final thoughts on CBD and the Immune System
The immune system also has a major role in neuroinflammatory and neurodegenerative conditions like strokes, head injuries and cerebral ischemia which is a condition in which there is an insufficient flow of blood to the brain. CBD has been used to provide both neurogenesis as well as neurodegeneration which leads to the promotion of new and degeneration of nervous tissues of the brain. The research that concluded these findings was however conducted on animals, more evidence is needed in order to prove the significant effects.
CBD’s capacity to act as an immunosuppressor means that it can have a beneficial therapeutic effect when the immune system is weakened or becomes hyperactive. There are indications that the mechanisms of how CBD interacts with the immune system involve the direct suppression of the activation of numerous immune cell types, the induction of apoptosis and promotion of regulatory cells. These actions therefore control immune cell targets.