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There is still a lot to learn about CBD, but thus far, dozens of studies and trials have shown that CBD oils and other CBD products may be effective in treating pain and inflammation for short and long-term relief.
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Being able to know exactly what a CBD oil contains invokes trust and peace of mind for consumers, especially those who are new to using CBD products.
Three well-vetted studies provide the basis of support for the FDA’s decision. In these trials, 516 patients with Lennox-Gastaut syndrome or Dravet syndrome received either Epidiolex or a placebo. Epidiolex, when taken along with other prescribed medications, decreased the frequency of participants’ seizures compared to the placebo.
In one such study, researchers administered CBD to people with heroin use disorder. Over the course of a week, CBD significantly reduced heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate and salivary cortisol levels. No serious adverse effects were found.
3. Reduce PTSD Symptoms
CBD’s ability to calm is perhaps its most popular effect and the reason its use is so widespread. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Some received a placebo while others received either 150 milligrams, 300 milligrams or 600 milligrams of CBD before their speeches. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. Interestingly, participants who received either 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligrams group.
Amyotrophic lateral sclerosis (ALS) is a disease that causes nerve cells in the brain and spinal cord to deteriorate, resulting in loss of muscle control that worsens over time. It’s not yet understood exactly why ALS occurs, although it can be hereditary in some cases. There’s no known cure, and there are only two FDA-approved medications to help treat ALS symptoms.
Meanwhile, at least one study in mice revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies.
Another cannabinoid drug, called Nabilone, is sometimes used to relieve sickness in people having chemotherapy for cancer.
Using cannabis while pregnant may harm the unborn baby. Cannabis smoke contains many of the same harmful chemicals found in cigarette smoke.
Read the latest updates on cannabis, cannabinoids and cancer – the evidence so far on the Cancer Research UK website.
Cannabis and pregnancy
Some examples include:
Cannabis contains active ingredients called cannabinoids. 2 of these – tetrahydrocannabinol (THC) and cannabidiol (CBD) – are the active ingredients of a prescription drug called Sativex. This is used to relieve the pain of muscle spasms in multiple sclerosis.
Cannabis also increases the risk of a relapse in people who already have schizophrenia, and it can make psychotic symptoms worse.
Cannabis use may affect fertility. Regular or heavy cannabis use has been linked to changes in the female menstrual cycle and lower sperm count, or lower sperm quality in men.