However, not everyone who has turned to CBD to help with their inflammation has experienced benefits.
“I have had IBD for over 20 years, and had been on a range of medications, from steroids to opioids,” Orr told Weedmaps. “The steroids helped a lot with inflammation but not with the pain, and the Oxy was like trying to crack a nut with a sledgehammer — brutal side effects. It made me feel awful due to bad nausea and extreme fogginess.”
Research using animal models has shown that CBD may be able to modulate the immune system. While CBD does not have much affinity for the body’s cannabinoid receptors, it does affect other receptors and targets. According to a 2018 study published in Neurology, CBD binds to and desensitizes receptors known to mediate pain and sensory perception, inflammation, and body temperature.
Woodcock emphasizes that while CBD seems to have potent anti-inflammatory qualities, THC does, too, and the two often work more effectively together. In her opinion, a full-spectrum medical cannabis product containing both THC and CBD will work faster due to THC’s direct effects on the receptors which control inflammation on the body.
“I have taken CBD to fight inflammation and have tried four different brands,” Allen explained. “I didn’t notice a difference with any of the brands. So, I prefer to use my other anti-inflammatories, like Plaquinel, low-dose naltrexone, and turmeric.”
CBD binds to and desensitizes receptors known to mediate pain and sensory perception, inflammation, and body temperature. Photo by: Gina Coleman/Weedmaps
A 2015 review published in Bioorganic and Medicinal Chemistry discussed the anti-inflammatory properties of CBD. The reviewers found that CBD reduces inflammation through several pathways in the body, and represents an effective potential treatment for a range of conditions characterized by inflammation.
There are also a few ‘natural’ remedies and suggestions about making changes to your diet. As a patient, when it comes to these types of conditions and the symptoms that come along with them, it can start to feel as though you have tried everything to fight it. CBD oil is a newer approach chronic inflammation and the pain associated with it.
There are two different types of inflammation, and these are acute and chronic. Acute inflammation is uncomfortable, but it is a good thing. This kind of inflammation is your body’s initial defense against any harmful stimuli. This does cause pain, redness, swelling, and heat, but it is a sign of a healthily functioning immune system.
At A Glance: CBD Oil that Helps with Inflammation
Types of Inflammation
If you have joint pain, plaque psoriasis, or you’re experiencing pain associated with any inflammatory condition, applying CBD cream or some other topical is a great option as well. This is a direct way to treat the pain you may be feeling because the cannabidiol can get to your CB2 receptors without having to go through your circulatory system. This can also help with the dry and irritated skin that can occur because of the restricted blood flow to the skin in those instances.
While some research suggests CBD may be able to help with inflammation, we’re still waiting for a final answer after more clinical trials are completed. However, the Joy Organics softgels that we recommend also contain curcumin, which has been shown to reduce inflammation. So you get all of the benefits of CBD in addition to the confidence that it will have the intended effect.
Inflammation is an important function of the human body because its primary purpose is to protect cells and initiate tissue repair. However, your body’s inflammatory response can range from inconvenient to excruciating. Even though it is a natural process, it does sometimes need to be treated as a health issue.
The type of inflammatory response that most people seek treatment for, and that you would use CBD oil for, is chronic inflammation. Chronic inflammation can be caused by a variety of conditions such as arthritis, lupus, IBS, or Crohn’s Disease. This type of inflammation causes your body to continually try and fight a perceived internal threat even if this inflammatory response isn’t necessary to heal you.
The endocannabinoid system is involved in key inflammatory processes, and it's vital for maintaining normal functioning of the nervous systems, immune system, and many other organs and tissues.
Some of the most common solutions for chronic pain and inflammatory diseases are NSAIDs, or nonsteroidal anti-inflammatory drugs (i.e. Advil), as well as acetaminophen drugs (i.e. Tylenol). But these pain-reducing pills have their own drawbacks, including possible negative long-term effects, which is why many people look for alternative treatment options to naturally ease pain and inflammation. (Related: What's the Best CBD Cream for Arthritis Pain?)
The inflammatory response is a natural defense mechanism that helps your body fight off pathogens and foreign compounds. There are two different types of inflammation: Acute, which lasts for short periods of time and occurs when cells or tissue in the body are damaged, and chronic, which can occur for months—or even years—and lead to harmful long-term effects on the body.
Does CBD for Inflammation Really Work?
Additionally, just like with any supplement, you should always check with your doctor before taking CBD, especially if you have a pre-existing medical condition or take prescription medications. Side effects are uncommon, but it's best to play it safe when it comes to your health and wellness. (Related: A Definitive List of the Proven Health Benefits of CBD Oil)
The effects of CBD are made possible primarily through cannabinoid receptors that are activated by the inflammatory response. Cannabinoids from hemp, like CBD, stimulate these same receptors, and in the process it can help modulate pain sensation and inflammation.
Recently, more and more people are turning to a new natural health alternative known as cannabidiol or CBD. By now, you may have heard of CBD, a cannabinoid found in hemp plants, as this buzzy new supplement is being touted for its wellness benefits for everything from anxiety to pain relief to skin care—and that includes the positive effects of CBD on inflammation. (Related: 3 Reasons You Should Try CBD Even If You Have No Interest In Weed)
According to a 2018 report by the Centers for Disease Control and Prevention, (CDC) one-fifth of the American adult population experiences chronic pain and inflammation on a daily basis. And for those who deal with inflammation, finding better long-term alternatives to over-the-counter NSAIDs can be another unexpected struggle all on its own.