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Sources:
King KM, Myers AM, Soroka-Monzo AJ, Tuma RF, Tallarida RJ, Walker EA, Ward SJ. “Single and combined effects of Δ 9 -tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain.” Br J Pharmacol. 2017 Sep;174(17):2832-2841.

I am undergoing chemotherapy for cancer, and a friend recommended I take CBD oil to help with the pain and nausea. Is it safe to do that, and does it work?

With medical cannabis now legal in 36 U.S. states, and cancer listed as a qualifying condition in many of them, it’s no wonder that more and more cancer patients are inquiring about using it, or its derivative cannabidiol (CBD). It’s also becoming more common for mainstream medical oncologists to consider recommending medical cannabis for their patients undergoing chemotherapy. Before you make any decisions about whether CBD or other forms of cannabis may be right for you, be sure to check with your doctor. Anything you take while undergoing chemotherapy could have unwanted or dangerous interactions with your chemo regimen, so don’t take CBD – or any other supplements or medications – without talking to your oncologist first.

Many patients have found that medical marijuana or its derivatives can help ease pain and nausea, especially those caused by chemotherapy, and the science supports that. In 2017, an ad hoc committee of the National Academies of Sciences, Engineering, and Medicine found strong evidence that cannabis or cannabinoids are effective for the treatment of chronic pain in adults and chemotherapy-induced nausea.

Aviram J, Lewitus GM, Vysotski Y, Uribayev A, Procaccia S, Cohen I, Leibovici A, Abo-Amna M, Akria L, Goncharov D, Mativ N, Kauffman A, Shai A, Hazan O, Bar-Sela G, Meiri D. “Short-Term Medical Cannabis Treatment Regimens Produced Beneficial Effects among Palliative Cancer Patients.” Pharmaceuticals (Basel). 2020 Nov 30;13(12):435.

Having said that, there have been some clinical trials of cannabinoids in treating cancer in humans that look promising, and more studies are planned. Although some of these investigations have concluded that THC and other cannabinoids such as CBD can help slow the growth or cause death in certain types of cancer cells, it would be premature to make changes in cancer protocols based on these results.

Petrovici AR, Simionescu N, Sandu AI, Paraschiv V, Silion M, Pinteala M. “New Insights on Hemp Oil Enriched in Cannabidiol: Decarboxylation, Antioxidant Properties and In Vitro Anticancer Effect.” Antioxidants (Basel). 2021;10(5):738. Published 2021 May 7.