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Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.

Remember, because CBD oils are largely unregulated, there is no guarantee that a product is either safe or effective.

This cannabis extract may help treat nerve pain, anxiety, and epilepsy

CBD is the short name for cannabidiol, one of the two chemicals—among the dozens in cannabis—that have the most health benefits. The other, tetrahydrocannabinol (THC), produces the psychoactive effects described as being “high.” CBD oil generally does not contain THC, although some trace amounts may be present in products sold in certain states.

CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.

In all but a few studies, lower doses of CBD (10 milligrams per kilogram, mg/kg, or less) improved some symptoms of anxiety. Higher doses (100 mg/kg or more) exhibited virtually no effect.

Topicals have a localized effect, impacting the skin where the cream or gel is absorbed. Once you settle on the best way to take cannabinoids to work for you, then you’ll need to play around with dosages.

Before learning how you can accurately measure your CBD dosage, it is important to introduce the concept of bioavailability and explore and compare different ways in which CBD can be consumed later in the article. This process will significantly assist you in selecting the optimal choice for your personal circumstances.

In this section, CBD dosage recommendations are provided for a wide variety of ailments based entirely on scientific research and expert opinion. CBD/THC dosages depend predominantly on the specific ailment with countless other factors playing a role. The same tends to be true when analyzing the timescale required for successful cannabinoid treatments.

So what is the best way to take CBD oil?

Eight epileptic patients and volunteers were administered a daily dose of 200-300 mg of CBD taken orally for four and a half months ( https://www.ncbi.nlm.nih.gov/pubmed/7413719 ). All patients and volunteers tolerated CBD very well. Half of them experienced excellent results and remained almost free of convulsive attacks throughout the experiment while three patients witnessed a partial improvement in their clinical condition. CBD treatment was ineffective for one of the patients.

However, there are some guidelines that can be used in order to estimate the CBD dosage necessary for your particular case depending on the relief you are seeking.

A review by Kluger et al. examines the basic science and preclinical and clinical studies on the therapeutic potential of cannabinoids as relating to movement disorders ( https://www.ncbi.nlm.nih.gov/pubmed/25649017 ). Hereby, multiple sclerosis studies reveal that a potentially effective treatment may utilize a cannabis plant extract containing 2.5-120 mg of a THC/CBD mixture to be taken daily for 2-15 weeks.

CBD oil behaves like most other drugs when inhaled. The lung gets it first and from there it’s sent via the bloodstream straight to the brain where it takes its effect, which is why inhalation is the fastest method for feeling the effects of CBD oil. From there, it will get metabolized by the liver.

“For individuals who have been paying close attention, they’re likely to be fine.”

(Recreational products will be similar in strength, format and pricing, said Canopy Growth vice-president Jordan Sinclair.)

Finding the right dose is very much a process of trial and error. Hence, we always recommend starting with a low dose and gradually building your way up until you hit a “sweet spot”. To help you achieve this, use the dosage guide below to know where to start.

Anxiety

CBD shows promise in the treatment of anxiety disorders, suggests a 2015 review of studies in the journal Neurotherapeutics.   According to the investigators, CBD demonstrated potent anxiolytic (anxiety-relieving) effects in animal research, albeit with counterintuitive results.

• Pain, both neuropathic and inflammatory
• Anxiety and stress
• Depression
• Chronic inflammation
• Appetite and metabolism
• Sleep
• Seizures and tremors
• Vomiting and nausea

Human studies evaluating the use of CBD in treating chronic pain are lacking. Those that do exist almost invariably include THC, making it difficult to isolate CBD’s distinct effects.

CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.