Trezza, et al. Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats. Psychopharmacology (Berl) 2008; 198(4): 529-537.
A. The FDA has approved Epidiolex, which contains a purified form of the drug substance CBD, for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients 1 years of age and older. It has also approved Epidiolex for the treatment of seizures associated with tuberous sclerosis complex in patients 1 year of age or older. That means the FDA has concluded that this particular drug product is safe and effective for its intended use. Controlled clinical trials testing the safety and efficacy of a drug, along with careful review through the FDA’s drug approval process, is the most appropriate way to bring cannabis-derived treatments to patients. Because of the adequate and well-controlled clinical studies that supported this approval, and the assurance of manufacturing quality standards, prescribers can have confidence in the drug’s uniform strength and consistent delivery that support appropriate dosing needed for treating patients with these complex and serious epilepsy syndromes.
A. Information for patients on Right to Try (RTT) is available on our website. RTT is designed to facilitate access to certain investigational drugs through direct interactions between patients, their physicians and drug sponsors – FDA is not involved in these decisions. Sponsors developing drugs for life-threatening conditions are responsible for determining whether to make their products available to patients who qualify for access under RTT. If you are interested in RTT, you should discuss this pathway with your licensed physician. Companies who develop drugs and biologics, also known as sponsors, can provide information about whether their drug/biologic is considered an eligible investigational drug under RTT and if they are able to provide the drug/biologic under the RTT Act.
Children and Pregnant/Lactating Women
The existence of substantial clinical investigations regarding THC and CBD have been made public. For example, two such substantial clinical investigations include GW Pharmaceuticals’ investigations regarding Sativex. (See Sativex Commences US Phase II/III Clinical Trial in Cancer Pain )
22. What does the FDA think about making CBD available to children with epilepsy?
18. How can patients gain access to cannabis or cannabis-derived products for medical use through expanded access?
Hemp seeds are the seeds of the Cannabis sativa plant. The seeds of the plant do not naturally contain THC or CBD. The hemp seed-derived ingredients that are the subject of these GRAS notices contain only trace amounts of THC and CBD, which the seeds may pick up during harvesting and processing when they are in contact with other parts of the plant. Consumption of these hemp seed-derived ingredients is not capable of making consumers “high.”
Josh Hurst is a journalist, critic, copywriter, and essayist. He lives in Knoxville, TN, with his wife and three sons. As a writer for Remedy Review, an independent CBD review site, Josh covers the relationship between cannabis-based products and the human body.
Another option for a CBD and hemp seed oil combo comes from Spruce, which makes its tinctures with a potent full-spectrum hemp extract. The Max Potency tincture is one of the strongest on the market, containing a total of 80 milligrams of CBD per serving—2,400 milligrams in total. Customers also have the freedom to choose either an MCT oil or hemp seed oil base for this particular product, or they can opt for the 750 milligram CBD oil for something a little less potent.
As you shop around for the best CBD oil, you'll find some CBD oils that also contain hemp seed oil for added benefits. The editors at Remedy Review, an independent CBD site, pulled together a list of CBD oils that contain hemp oil. These products come from top brands that have undergone an extensive review process that takes into account customer reviews, price, lab testing, hemp source, and more.
There are also some important distinctions in the way CBD oil and hemp seed oil are processed. The latter is usually made through cold-pressing hemp seeds to create a dark, thick oil that is highly concentrated and nutrient-rich. CBD oil, on the other hand, is made from different processes such as ethanol or CO2 extraction, which draw from the whole hemp plant and create a final product that contains more beneficial plant compounds, like cannabinoids and terpenes.
NuLeaf Naturals products contain USDA organic certified hemp seed oil, so you still get the added benefit of this nutrient-rich carrier oil in conjunction with CBD. Additionally, these full-spectrum CBD oils are some of the strongest on the market, containing 60 milligrams of CBD per milliliter. There are no additives within these high-quality CBD oils, and all products are thoroughly lab-tested with easily accessible Certificates of Analysis available online.
To begin with, be clear about whether you're actually looking for hemp seed oil, or if you want actual CBD. Make sure you thoroughly read product labels to ensure you're getting what you want. In particular, look for references to "CBD," "cannabidiol," or "full-spectrum hemp extract" on the ingredients list; if none are listed, then what you're looking at is probably hemp oil, and you shouldn't expect to receive CBD oil benefits from it. It's advisable to always spend time perusing the ingredient lists, as many hemp seed oils are misleadingly marketed to look like they are CBD products.
So, long story short: If you're looking for the most pronounced health benefits, you're better off purchasing true CBD oil as opposed to hemp (seed) oil, where CBD is minimal or non-existent and therefore cannot offer the same effects.