In addition, more trials are needed to investigate its use for numerous other conditions, such as muscle-spasticity in multiple sclerosis, Alzheimer’s disease, substance-abuse treatment, and diabetes protection.
Conclusion: Topical CBD may be beneficial at relieving arthritis but no high-quality human studies prove this.
Animal studies have shown that CBD has anti-inflammatory effects and works on the endocannabinoid and pain-sensing systems to relieve pain.
9. Nausea and vomiting
Conclusion: CBD shows promise for improving the quality of life in people with Parkinson’s disease but larger trials are needed.
CBD (short for cannabidiol) is one of over 200 chemical compounds known as cannabinoids that are found in cannabis. It is the second most prevalent active compound found in cannabis, behind THC (tetrahydrocannabinol), which is the compound in cannabis that has psychoactive properties and gives people a high. 2
We look at nine medical conditions where CBD may be, or, has already proven to be, beneficial.
Unlike THC, CBD has no psychoactive properties and will not give you a “high”. There is no evidence it has any abuse or dependence potential and to date, there is no evidence that it is associated with any serious side effects, according to the World Health Organization.
Proponents claim that CBD oil can treat a wide variety of health problems, including:
CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.
The tricky part is calculating the exact amount of CBD per milliliter of oil. Some tinctures have concentrations of 1,500 mg per 30 mL, while others have 3,000 mg per mL (or more).
CBD oil should be avoided during pregnancy and breastfeeding. A 2018 study from the American Academy of Pediatrics warned women to avoid marijuana during pregnancy due to the potential risks to a baby’s development. Although it is unclear how CBD contributes, CBD is known to pass through the placental barrier.
According to the investigators, men provided 300 mg of CBD exhibited less anxiety than those given a placebo. Interestingly, those provided 100 mg or 600 mg of CBD oil did not.